TFAP2A,AP-2 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
TFAP2A,AP-2 抗体

TFAP2A,AP-2 抗体

商家询价

产品名称： TFAP2A,AP-2 抗体

英文名称： TFAP2A,AP-2 Antibody

产品编号： XY13019-3

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 TFAP2A,AP-2 抗体Applications

In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Published applications ChIP, WB Publications 1 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human, mouse
Images
Prev1NextView more validation data
  • 13019-3-AP;MCF7 cellsMCF7 cells were subjected to SDS PAGE followed by western blot with 13019-3-AP(TFAP2A,AP-2 antibody) at dilution of 1:300
Positive WB detected in MCF7 cells, HeLa cells
Recommended dilution WB : 1:200-1:2000
TFAP2A,AP-2 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen TFAP2A,AP-2 fusion protein ag4112 Full name Transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Calculated molecular
weight		 431aa,47 kDa Observed molecular 
weight		 47 kDa
GenBank accession 
number		 BC017754 Gene ID (NCBI) 7020
Gene symbol TFAP2A Synonyms Activator protein 2, AP 2, AP 2 transcription factor, AP 2alpha, AP2, AP2 alpha, AP2TF, BOFS, FLJ51761, TFAP2, TFAP2A
BackgroundTFAP2A,AP-2 抗体

The activator protein-2 (AP-2) family of transcription factors comprises five 52-kDa isoforms (AP-2α, AP-2β, AP-2γ, AP-2δ, and AP-2ε), which share a common structure: a proline/glutamine-rich transactivation domain in the N-terminal region and a helix-span-helix domain in the C-terminal region, which mediates dimerization and site-specific DNA binding. Depending on the cellular context, the AP-2 transcription factors are individually associated either with cell differentiation and development or with cancer progression/regression. [PMID:21966377] TFAP2A (AP-2-alpha) is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation [PMID:11694877]TFAP2A,AP-2 抗体

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