Recombinant human IL1A
产品名称: Recombinant human IL1A
英文名称: Recombinant human IL1A
产品编号: IL1A-501H
产品价格: 0
产品产地: USA
品牌商标: Creative Biomart
更新时间: null
使用范围: null
- 联系人 :
- 地址 : 北京市通州区经海五路1号院22号楼
- 邮编 :
- 所在区域 : 北京
- 电话 : 158****7462 点击查看
- 传真 : 点击查看
- 邮箱 : info@abace-biology.com
http://www.creativebiomart.net/description_388443_12.htm
Interleukin-1 alpha (IL1a) is also known as IL-1A, IL1, IL1-ALPHA,IL1F1,and is a cytokine of the interleukin-1 family. IL1a possesses a wide spectrum of metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. IL-1α is constitutively produced by epithelial cells. It is found in substantial amounts in normal human epidermis and is distributed in a 1:1 ratio between living epidermal cells and stratum corneum.The constitutive production of large amounts of IL-1α precursor by healthy epidermal keratinocytes interfere with the important role of IL-1α in immune responses, assuming skin as a barrier, which prevents the entry of pathogenic microorganisms into the body. In vitro, IL-1α possesses biological effect on cells in the picomolar to femtomolar range. In vivo, Shortly after an onset of an infection into organism, IL-1α activates a set of immune system response processes.