AKT3 (phospho S472) Peptide
产品名称： AKT3 (phospho S472) Peptide
英文名称： AKT3 (phospho S472) Peptide
产品编号： P1602
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of AKT3.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S472 of human AKT3.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Peptide affinity purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Transforming growth factor-beta1 stimulated protein kinase B serine-473 and focal adhesion kinase tyrosine phosphorylation dependent on cell adhesion in human hepatocellular carcinoma SMMC-7721 cells.
Xu Z, Ma DZ, Wang LY, Su JM, Zha XL.Biochem Biophys Res Commun. 2003 Dec 12;312(2):388-96.
- 2.
- Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance.
Brozinick JT Jr, Roberts BR, Dohm GL.Diabetes. 2003 Apr;52(4):935-41.
- 3.
- Gene expression profiling in prostate cancer cells with Akt activation reveals Fra-1 as an Akt-inducible gene.
Tiwari G, Sakaue H, Pollack JR, Roth RA.Mol Cancer Res. 2003 Apr;1(6):475-84.
- Entrez GeneID:
- 10000
- Protein Accession#:
- NP_005456;Q9Y243
- Gene Name:
- AKT3
- Gene Alias:
- DKFZp434N0250,PKB-GAMMA,PKBG,PRKBG,RAC-PK-gamma,RAC-gamma,STK-2
- Gene Description:
- v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
- Omim ID:
- 611223
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq
- Other Designations:
- OTTHUMP00000037911,OTTHUMP00000037912,RAC-gamma serine/threonine protein kinase,protein kinase B gamma,serine threonine protein kinase, Akt-3,v-akt murine thymoma viral oncogene homolog 3
- Interactome
- Gene Pathway
- Acute myeloid leukemia
- Adipocytokine signaling pathway
- Apoptosis
- B cell receptor signaling pathway
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Colorectal cancer
- Endometrial cancer
- ErbB signaling pathway
- Fc epsilon RI signaling pathway
- Fc gamma R-mediated phagocytosis
- Focal adhesion
- Glioma
- Insulin signaling pathway
- Jak-STAT signaling pathway
- MAPK signaling pathway
- Melanoma
- mTOR signaling pathway
- Neurotrophin signaling pathway
- Non-small cell lung cancer
- Pancreatic cancer
- Pathways in cancer
- Prostate cancer
- Renal cell carcinoma
- Small cell lung cancer
- T cell receptor signaling pathway
- Tight junction
- Toll-like receptor signaling pathway
- VEGF signaling pathway